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", Contemporary Clinical Trials Communications: "Preliminary Analysis of the Effect of Stevia (Stevia rebaudiana) in Patients With Chronic Kidney Disease (Stage I to Stage III)", Physiology & Behavior: "Metabolic Effects of Non-Nutritive Sweeteners", Canadian Medical Association Journal: "Nonnutritive Sweeteners and Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Prospective Cohort Studies", Memorial Sloan Kettering Cancer Center: "Stevia", Food and Chemical Toxicology: "Steviol Glycoside Safety: Are Highly Purified Steviol Glycoside Sweeteners Food Allergens? Cardiovascular health: Insomnia linked to greater risk of heart attack. Automatic detention of stevia leaves, extract of stevia leaves, and food containing stevia. Currently, researchers have only explored the potentially positive aspects of this use. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Melis MS. https://www.fda.gov/ora/fiars/ora_import_ia4506.html (Accessed 21 April 2004). Some research on long-term, daily use of artificial sweeteners suggests a link to a higher risk of stroke, heart disease and death overall. Taware, A. S., Mukadam, D. S., and Chavan, A. M. Antimicrobial Activity of Different Extracts of Callus and Tissue Cultured Plantlets of Stevia Rebaudiana (Bertoni). Verywell Health's content is for informational and educational purposes only. Yadav, A. If youre trying to lose weight, this aspect may be appealing. stomach discomfort or upset. While stevia is generally considered safe to be used in food and drink, some extracts of the plant have not been approved by the Food & Drug Administration (FDA). You should add extra liquid or a bulking ingredient such as applesauce or mashed bananas to your recipe to make up for the lost sugar. The Best Sugar Substitutes for People with Diabetes. However, research supporting the safe use of less refined stevia compounds is still lacking. While that high level of consumption is not generally recommended, it demonstrates the vast volume of stevia you would need to consume for it to be considered unsafe. The Pros and Cons of Artificial Sweeteners, Artificial Sweeteners and Type 2 Diabetes. (2018). Saudi Pharmaceutical Journal. If you have a bowel disease. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. https://www.fda.gov/food/food-additives-petitions/additional-information-about-high-intensity-sweeteners-permitted-use-food-united-states. According to a 2020 review, "In addition to its hypoglycemic property, the stevia plant also exhibits antibacterial, anti-inflammatory, hypotensive, antiseptic, diuretic, anti-fertility and cardiotonic properties." Below are some of the main advantages associated with stevia use: 1. It's possible that different types of products may cause stevia stomach upset more than others. Click here for an email preview. Stevia can also interact with certain medications, so it is important to discuss stevia with a doctor before consuming or purchasing the product. Heuberger R. Overview of non-nutritive sweeteners. All rights reserved. Acesulfame potassium (Sweet One, Sunett). Taking stevia along with medications that lower blood pressure might cause blood pressure to go too low.